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Ghent University Hospital |
1) Pharmacological research
- Pharmacokinetics and dynamics of AQUAVAN™ Injection, a Water-Soluble Prodrug
of Propofol as a Bolus Injection : A Phase I Dose Escalation Comparison with
DIPRIVAN©
- Pharmacodynamic properties of inhaled anesthetics during anesthesia in morbidly
obesitas.
- Pharmacokinetic/dynamic controlled administration of opiates during anesthesia in
morbidly obesitas.
- Onset dynamics of inhaled anesthetics during induction of anesthesia.
- Optimization of intravenous drug administration in out-OR anesthesia procedures
- Closed-loop control of hypnotics by model-based controllers and BIS.
2) Physiologicial research :
- One lung ventilation during anesthesia
- Physiological changes during intracranial ventriculoscopic procedures
3) Medical equipment testing and validation :
- Accuracy of bispectral index (BIS), mid-latency auditory evoked potentials (MLAEP-
AAI) and spectral entropy (SE and RE) to measure depth of anesthesia
- Safety of different sodalimes during low flow anesthesia. (Compound A and CO
toxicity)
- Influence of anesthesia ventilator design on the pharmacological characteristics of inhaled
- Accuracy of various syringe pumps when controlled by external computer software.
(Lab validation of flow accuracy)
- Comparison of the accuracy of various airway devices during anesthesia.